sensitivity and specificity example questions

sensitivity and specificity example questions


Therefore it is 98823/99220=0.996 to 3 decimal places.

Order Original Answers for all your Classes, Total – (TP + FN) = FP + TN = 300 – 100 = 200, predictive value (+) and predictive value (–). A test-retest reliability study of the new test was conducted with the following results: What is the percentage agreement (accuracy)?

2012;61:41–45. What factors should govern the selection and use of a screening instrument by a health clinic? The specificity is more problematic because PSA blood levels can be elevated for other reasons besides cancer. 1971;27:3–8. Please go back and complete the questions. Commission on Chronic Illness. Beaglehole R, Bonita R, Kjellström T. Basic Epidemiology.

What is the predictive value of a negative test.
A new test was compared with a gold standard measurement with the following results: What are the sensitivity and specificity? New York, NY: Oxford University Press; 1986.

The PPV of the test focuses on the Test+ row of the table.

Week 8 e-Activity Go to your state’s DOH Website, and review the statistics and research data information on screening for cancer and other prevalent diseases. Figure 11–5 illustrates the relationship between sensitivity and specificity.

Men found to have prostate cancer—about 25% to 35% of men biopsied—have a number of options. In the United States, most men opt for one of several available treatments for prostate cancer.

Another approach, although less rigorous, is to conduct ecologic time trend studies in geographic areas with and without screening programs. Am J Optom Physiol Opt.

Report the answer to 3 decimal places.

A subject may have an elevated glucose level in the high range for a population (e.g., 120 mg/dL) and not be diabetic. The answer is 0.996. The answer is 0.488. We provide step-by-step answers to all writing assignments including: essay (any type), research paper, argumentative essay, book/movie review, case study, coursework, presentation, term paper, research proposal, speech, capstone project, annotated bibliography, among others. The table below shows the results from looking at the diagnostic accuracy of a new rapid test for HIV in 100,000 subjects, compared to the Reference standard ELISA test. Three hundred individuals were referred to a laboratory for testing. International Statistical Classification of Diseases and Related Health Problems. 13th ed. New York, NY: Wiley; 1961. Geneva, Switzerland: World Health Organization; 1968. We Will Help You Write Your Essays

Geneva, Switzerland: World Health Organization; 1971. The ideal design is a randomized controlled trial.

This chapter discussed terminology related to the quality of measures employed in epidemiology. Report the answer to 5 decimal places. MMWR. Hurley SF, Kaldor JM. Men with suspicious PSA levels may go on to have a prostate biopsy. It is the number of truly HIV+ patients who tested positive with the new rapid test divided by the total number of positive tests using the new rapid test. Mass Health Examinations. Classification, in contrast, lends itself to the statistical compilation of groups of cases of disease by arranging disease entities into categories that share similar features.21. The classifications of disease must be distinct so that a disease falls into only one category of the classification system. 1984;61:359–360. Click the Next button to begin the quiz.

The NPV of the test focuses on the Test- row of the table.

The terms nomenclature and classification are defined as follows: A nomenclature is a highly specific set of terms for describing and recording clinical or pathologic diagnoses to classify ill persons into groups.

Cancer screening–United States, 2010. The PPV is 95.74. 4th ed. Indeed, many of the issues remain controversial, as noted in Exhibit 11–1 for mammography screening and Exhibit 11–4 for the prostate-specific antigen (PSA) test. C to D, survival time for unscreened case; B to D, survival time for screened case; B to C, lead time. Cochrane AL, Holland WW. After comparing those harms to the benefit of saving one life, the U.S. Preventive Services Task Force calculated that the harms of PSA screening outweigh the benefits. Specificity will be lowered because more of the nondiseased individuals will be classified as diseased. Using the data from question 7, what is the predictive value (+) and the predictive value (–)? Thus, this example demonstrates that sensitivity and specificity are complementary. Page 1/3. Controversy in the detection of disease.

There are a number of additional procedures that can improve both sensitivity and specificity: Despite the intuitive appeal of screening programs, their utility should never be assumed. Chronic Illness in the United States: Prevention of Chronic Illness. PSA is a molecule found in cells that make up the prostate gland and is released when tumors disrupt the prostate cells. McCunney RJ.

If you'd like to print a Certificate of Completion, enter your name and click the button. How to Land the Job and Knock the Socks off Your Interviewer, A List of Fellowships in Clinical Informatics, The Basics of Healthcare Economics for the Clinical Informatics Exam, Practice Question of the Week: IOM Quality Aims, Be a Better Clinical Informaticist: 3 Tips to Look Awesome at Work in Just 2 Minutes, Sample Job Description for a Clinical Informatics Position, How To Do a Failure Modes and Effects Analysis (plus bonus practice question). How does the predictive value of a screening test vary according to the prevalence of disease? From initial topic to finished paper. Formulas and examples for calculation of sensitivity, specificity, and predictive value were provided. 1981;124:703–710. Please remember to click the Submit button for each separate question, and read the feedback comments! Therefore it is 378/380=0.995 to 3 decimal places. It is the number of truly HIV- patients who tested negative with the new rapid test divided by the total number of negative tests using the new rapid test. Calculate the sensitivity, specificity, and predictive value of this test.

Finally, the case-control method can be applied also: Cases are fatal (or likely to be fatal) cases of the disease, controls are nonfatal cases of the disease, and the exposure is participation in a screening program. 20 By using the criterion of 15 mm Hg intraocular pressure, the sensitivity of the screening test would be high, and few persons with glaucoma would be missed.

When the prevalence of a disease decreases the predictive value (+) falls and the predictive value (–) rises. Some diabetic individuals who are at the lower end of the curve for the diseased group also may have glucose levels in the high normal range. 4.

Geneva, Switzerland: World Health Organization; 2004. The rows of the table represent the test result and the columns the true disease status (as confirmed by ELISA). Baltimore, MD: Johns Hopkins University Press; 1988. Haynes RB.

The use of general categories facilitates the epidemio-logic study of disease phenomena by giving rise to groups of interrelated morbid conditions. A serologic test yielded 200 positives, of which one-fourth were true positives.

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